This book is the second of several volumes on solids in the Shock Wave Science and Technology Reference Library. These volumes are primarily concerned with high-pressure shock waves in solid media, including detonation and high-velocity impact and penetration events. Of the four extensive chapters in this volume, the first two describe the reactive behavior of condensed phase explosives, – Condensed-Phase Explosives: Shock Initiation and Detonation Phenomena (SA Sheffield and R Engelke) – First Principles Molecular Simulations of Energetic Materials at High-Pressures (F Zhang, S Alavi, and TK Woo), and the remaining two discuss the inert, mechanical response of solid materials. – Combined Compression and Shear Plane Waves (ZP Tand and JB Aidun), and – Dynamic Fragmentation of Solids (D Grady). All chapters are each self-contained, and can be read independently of each other. They offer a timely reference, for beginners as well as professional scientists and engineers, on the foundations of detonation phenomena, high strain rate response behavior, and on the burgeoning developments as well as challenging unsolved problems.
The first standard reference on chronopharmaceutics
As we better understand how biological processes unfold in real time through advances in chronobiology and related fields, we can create safer, more effective drugs, drug delivery systems, and disease monitoring and prevention systems. When administered in correct coordination with a patient’s body rhythms, such drugs can maximize therapeutic outcome while minimizing unwanted side effects. Chronopharmaceutics presents the first standard reference text on this emerging cross-disciplinary field and its potential for therapeutic and preventive medicine.
Bringing together the latest findings from experienced investigators, this edited work presents a much-needed single source on chronopharmaceutics. After an introduction that includes a timeline of key discoveries, an overview of regula-tory, formulation, manufacturing and key resource issues associated with chronopharmaceutics, the detailed coverage examines:
Controlled release systems triggered by physical and/or chemical activation
Chronopharmacodynamics, chronomics, and anesthesia
Filling a gap in both the graduate classroom and the working industrial or research laboratory, Chronopharmaceutics offers students, instructors, and professionals a unique and comprehensive reference for this cutting-edge field.
Brian Falkner delivers in this sci-fi thriller with a Da Vinci Code twist! It begins with a book. The most boring book in the world. A book so boring no one could ever read it—the perfect place to hide a dangerous secret. When best friends Luke and Tommy volunteer to help move books from their library’s basement to higher ground during a quick-rising flood, they discover the only surviving copy of the world’s most boring book: Leonardo’s River, lost for over a hundred years. Mysteriously connected to Leonardo da Vinci, the book is worth millions, so Luke and Tommy return that night to steal it. Unfortunately, they’re not the only ones with that plan. . Brian Falkner, author of The Assault, Brain Jack, and The Tomorrow Code, weaves another page-turning thriller full of heart-pounding action–this time, with a secret from Leonardo da Vinci that could determine the fate of history. Hand this to a reluctant boy reader or any reader who loves action and mystery. “Falkner delivers a thriller that melds humor, danger and history. . . . The result is an entertaining mystery with plenty of enjoyable twists and turns.”
Cecilia Undergarment likes a challenge. So when she discovers a sad and neglected dog, she is determined to rescue him. But her daring dog rescue lands her lost and alone in the dark forest of Northwood. A forest where ferocious black lions roam. A forest where those who enter never return. But then Northwood has never seen the likes of Cecilia Undergarment before…
Jacob is tired of getting into trouble. He’s fed up with being pushed around and hassled by Blocker – the school bully. But then he discovers he has a special power. Will he use it to be a superhero? Or a supervillain? Either way, life for Jacob is never going to be the same. A mind-bending adventure.